Found 78 matching trials
VX-770 Expanded Access Program N/A The purpose of this expanded access program is to provide VX-770 prior to i...
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A Study Evaluating the Long-term Safety and Efficacy of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis (CF) Particpants 6 Years and Older and F/MF Genotypes PHASE3 The study evaluates the long-term safety and efficacy of elexacaftor (ELX)/...
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Telethon Kids Institute
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The Topic Trial - Study to Determine the Safety and Efficacy of Ivacaftor PHASE2 The study is a Phase 2 Study to establish the safety and efficacy of a drug...
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UAB Lung Health Center
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A Phase 2 Study to Evaluate Effects of VX-661/Ivacaftor on Lung and Extrapulmonary Systems in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation PHASE2 To evaluate the clinical mechanisms of action in lung and extrapulmonary sy...
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Multiple Locations
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A Study Evaluating the Safety and Efficacy of VX-659 Combination Therapy in Subjects With Cystic Fibrosis PHASE2 This is a Phase 2, randomized, double-blind, placebo- and tezacaftor/ivacaf...
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Yale New Haven Hospital
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A Study to Assess the Effect of ELX/TEZ/IVA on Glucose Tolerance in Participants With Cystic Fibrosis (CF) PHASE3 This study was evaluate the effect of elexacaftor (ELX)/tezacaftor (TEZ)/iv...
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Royal Adelaide Hospital
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Study to Evaluate Safety, Tolerability and PK of C-10355 and C-10358 in Healthy Subjects PHASE1 This two-part study will assess, in healthy volunteers, under both fasted a...
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Safety Study of Ivacaftor in Subjects With Cystic Fibrosis PHASE2 The purpose of this study was to evaluate the safety and tolerability of iv...
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University of Alabama Hospital
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Rollover Study of VX-770 in Cystic Fibrosis Subjects PHASE3 The primary objective of the study was to evaluate the safety of long-term ...
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Multiple Locations
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Clearing Lungs With ENaC Inhibition in Primary Ciliary Dyskinesia PHASE2 To evaluate the safety and efficacy of treatment with VX-371 with and witho...
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Multiple Locations
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